In a recent study, published in the journal Hypertension, Monash Health’s Dr Jun Yang and a team of researchers at the Hudson Institute of Medical Research, University of WA and Baker Institute, found that the effects of aldosterone are different in young males and females.
Primary aldosteronism, which is caused by the increased production of a hormone called aldosterone, is a common, potentially curable form of high blood pressure. However, it is often neglected. Through her research, Dr Yang shared that primary aldosteronism can be detected with a simple blood test even in the early stages of hypertension, and that early intervention with targeted treatment can be highly beneficial.
Dr Jun Yang is a Consultant Endocrinologist at Monash Health, Head of the Endocrine Hypertension Group at the Hudson Institute of Medical Research, and a Senior Postdoctoral Fellow within the School of Clinical Sciences at Monash University.
The research was the first time that the relationship between gender, aldosterone levels and blood pressure has been studied in a large group of young people.
The study found that aldosterone levels were related to blood pressure at the age of 17 in males, but not in females. For females, their aldosterone levels at 17 were related to their blood pressure at 27.
Dr Yang explained that these findings would help inform the earlier diagnosis and targeted treatments of aldosterone-mediated high blood pressure, leading to better control of blood pressure and improved health outcomes for those at risk.
Dr Yang reiterated the importance of this research, as most patients with primary aldosteronism are diagnosed later in life. With an earlier diagnosis, tailored treatment can be commenced early to block the harmful effects of aldosterone on the heart, kidney and blood vessels.
To learn more about Dr Yang and her research, visit her profile on the Hudson Institute of Medical Research website.
Approved by Anjali Dhulia.